Faculty

Wei-Chuan Shih
Dr. Wei-Chuan Shih
Associate Professor
Office Location: W328 Engineering Building 2
Phone: 713-743-4454 | Fax: 713-743-4444
Email: wshih [at] uh [dot] edu
Website: http://nanobiophotonics.ee.uh.edu
DotLens Smartphone Microscopy on PBS

Education: 

Ph.D., MIT

Professional Experience: 

Associate Professor, Electrical & Computer Eng (Primary)/ Biomedical Eng/Materials Science & Eng/Chemistry, 2009-present
Schlumberger Research Fellow, Schlumberger-Doll Research, 2007-2009

Classes: 

ECE 6342 Digital Signal Processing
ECE 6338 Optical and Ultrasonic Imaging
ECE 6397 Special Topics: Optical Imaging and Spectroscopy
ECE 3337 Electrical Engineering Analysis/ Signals & Systems
ECE 6339 Biophotonics

Awards & Honors: 

MIT Martin Fellowship for Sustanability, MIT, 2005
NSF CAREER Award, NSF, 2012
NASA Early Career Faculty Award, NASA, 2012
UH Award of Excellence in Research and Scholarship, University of Houston, 2013
NIH Study Section Instrumental and System Development, National Institute of Health, 2011-
NSF Regular and SBIR panels, National Science Foundation
UH Cullen College of Engineering Research Award, 2015

Research Interests: 

Nanobiophotonics: Plasmonics, Surface-enhanced Raman spectroscopy, Nanofabrication, Nanofluidics

Hyperspectral imaging: Raman/SERS microscopy, Two-photon fluorescence lifetime imaging, Active/structured illumination microscopy, Compressive sensing imaging

Microsystems: N/MEMS, Lab-on-a-chip

Plasmonic Engineering: Hierarchical nanoporous gold (HNPG), Label-free DNA biomarker sensing, Intracellular sensor network, Molecular trapping, Photodynamic and photothermal therapy, Gene therapy

Novel Hyperspectral Imaging: Active/structured illumination, Computational multispectral Infrared imaging

Neural Probe for Deep Brain Stimulation and Recording: Flexible Optitrode with integrated optical and electrical channels.

Environmental Sensing: water quality, pathogen, oil spill

Smartphone microscopy: bright/dark-field, fluorescence

Funded Research: 

NSF CAREER Award 2012
NASA CAREER Award 2012
GoMRI-RFPII 2012
NIH R21 2014
Department of Interior BSEE 2015
NSF I-CORPS 2015
NSF CBET Nano-Biosensing 2016
NSF EAGER: Citizen Science 2016

Selected Publications: 

Book chapters and magazine articles
1. Wei-Chuan Shih, “Hybrid fabrication makes better plasmonic nanostructures for SERS,” Photonics Spectra, August, 2013.
2. Wei-Chuan Shih, Kate L. Bechtel, and Michael S Feld, “Quantitative Biological Raman Spectroscopy,” in Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues, Editor:  Valery V. Tuchin; Taylor & Francis (2008).
3. Wei-Chuan Shih, Kate L Bechtel, Michael S Feld, Mark A Arnold, Gary W Small, “Introduction to spectroscopy for noninvasive glucose sensing,” in Analytical Chemistry of In Vivo Glucose Measurements; Cunningham, D.; Stenken, JA, Eds.; Wiley Chemical Analysis Series (2009).
4. Wei-Chuan Shih, Kate L Bechtel, Michael S Feld, “ Non-invasive glucose sensing with Raman spectroscopy,” in Analytical Chemistry of In Vivo Glucose Measurements; Cunningham, D.; Stenken, JA, Eds.; Wiley Chemical Analysis Series (2009).

Refereed journal publications (Published after 2009)
1. Jae Won Jeong, Md Masud Parvez Arnob, Kwang-Min Baek, Seung-Yong Lee, Wei-Chuan Shih, and Yeon Sik Jung, Three-dimensional Cross-point Plasmonic Nano-architectures Containing Dense and Regular Hot Spots for Surface-Enhanced Raman Spectroscopy Analysis, Advanced Materials, 2016. (DOI: 10.1002/adma.201602603)
2. Wei-Chuan Shih*, Greggy Santos, Fusheng Zhao, Oussama Zenasni, and Masud Arnob, Simultaneous chemical and refractive index sensing in 1-2.5 μm wavelength range on nanoporous gold disks, Nano Letters, 16 (7): 4641–4647 2016.
3. Greggy Santos, Felipe Ibañez de Santi Ferrara, Fusheng Zhao, Debora F. Rodrigues, and Wei-Chuan Shih, Photothermal inactivation of heat-resistant bacteria on nanoporous gold disk arrays, Optical Materials Express 6(4): 1217-1229 2016.
4. Jingting Li, Yong Du, Ji Qi, Ravikumar Sneha, Anthony Chang, Chandra Mohan, Wei-Chuan Shih*, Raman spectroscopy as a diagnostic tool for monitoring acute nephritis, Journal of Biophotonics 9(3): 260-269 2015.
5. Yu-Lung Sung, Jenn Jeang, Chia-Hsiung Lee, and Wei-Chuan Shih*, Fabricating optical lenses by inject printing and heat-assisted in situ curing of polydimethylsiloxane for smartphone microscopy, Journal of Biomedical Optics 20(4): 047005 2015.
6. Wei-Chuan Shih*, Kate L Bechtel, and Mihailo Rebec, Non-invasive glucose sensing by transcutaneous Raman spectroscopy, Journal of Biomedical Optics 20(5): 051036 2015.
7. Ming Li, Yong Du, Fusheng Zhao, Jianbo Zeng, Chandra Mohan, and Wei-Chuan Shih*, Reagent- and separation-free measurements of urine creatinine concentration by stamping surface-enhanced Raman scattering (S-SERS), Biomedical Optics Express 6(3): 849-858 2015.
8. Greggy Santos, Fusheng Zhao, Jianbo Zeng, Ming Li, and Wei-Chuan Shih*, Zepto-mole cancer marker detection by surface-enhanced fluorescence on nanoporous gold disk substrates, Journal of Biophotonics 8(10): 855-863 2015.
9. O Khantamat, CH Li, F Yu, AC Jamison, WC Shih, C Cai and TR Lee, Gold nanoshell-decoraed silicone surfaces for the NIR photo thermal destruction of the pathogenic bacterium E. faceless, ACS Applied Materials & Interfaces 7(7): 3981-3993 2015.
10. Peter Liu, Ji Qi, Wei-Chuan Shih*, and Kirill Larin*, Improvement of tissue analysis and classification using Optical Coherence Tomography combined with Raman spectroscopy, Journal of Innovative Optical Health Sciences 8(2): 1550006, 2015.
11. Fusheng Zhao, Jianbo Zeng, and Wei-Chuan Shih*, In situ patterning of hierarchical nanoporous gold structures by in-plane dealloying, Materials Science and Engineering B 194:34-40, 2015.
12. Ji Qi, Pratik Motwani, Jianbo Zeng, John C. Wolfe, and Wei-Chuan Shih*, Morphological, plasmonic, and SERS characterization of DC-sputtered gold nanoislands, Biomedical Spectroscopy and Imaging 4(1): 95-103, 2015.
13. Wei-Chuan Shih*, Constrained regularization for non-invasive glucose sensing using Raman spectroscopy, Journal of Innovative Optical Health Sciences 8(4): 1550022. 2015.
14. Jianbo Zeng, Fusheng Zhao, Ming Li, Chien-Hung Li, T. Randall Lee, and Wei-Chuan Shih*, Morphological control and plasmonic tuning of nanoporous gold nanoparticles by surface modifications, Journal of Materials Chemistry C 3:247-252, 2015.
15. Ji Qi, Kate L Bechtel, and Wei-Chuan Shih*, Automated image curvature assessment and correction for high-throughput Raman spectroscopy and microscopy, Biomedical Spectroscopy and Imaging 3(4): 359-368, 2014.
16. Md Masud Parvez Arnob, Fusheng Zhao, Jianbo Zeng, and Wei-Chuan Shih*, Laser rapid thermal annealing enables tunable plasmonics in nanoporous gold nanoparticles, Nanoscale 6(21), 12470-12475, 2014.
17. Narendran Sudheendran, Ji Qi, Eric D. Young, Alexander J. Lazar, Dina C. Lev, Raphael E. Pollock, Kirill V. Larin, Wei-Chuan Shih*, High throughput Raman spectral imaging complements optical coherence tomography for tumor boundary detection, Laser Physics Letters 11:105602, 2014 (*: Equal contribution).
18. Jianbo Zeng, Ji Qi, Fuquan Bai, Jorn Yu, and Wei-Chuan Shih*, Analysis of ethyl and methyl centralite vibrational spectra for mapping organic gunshot residue, Analyst 139(17), 4270-4278, 2014.
19. Jianbo Zeng, Fusheng Zhao, Chien-Hung Li, Yifei Li, Yan Yao, T. Randall Lee, and Wei-Chuan Shih*, Internal and external morphology-dependent plasmonic properties in nanoporous gold disks, RSC Advances 4, 36682-36688, 2014.
20. Ming Li, Fusheng Zhao, Jianbo Zeng, Ji Qi, Jing Lu, and Wei-Chuan Shih*, Microfluidic surface-enhanced Raman scattering (SERS) sensor with monolithically integrated nanoporous gold disk (NPGD) arrays for rapid and label-free biomolecular detection, Journal of Biomedical Optics 19(11), 111611, 2014.
21. Ji Qi, Jianbo Zeng, Fusheng Zhao, Steven Hsesheng Lin, Balakrishnan Raja, Ulrich Strych, Richard C. Willson, and Wei-Chuan Shih*, Label-free, in situ SERS monitoring of individual DNA hybridization in microfluidics, Nanoscale 6(15), 8521-8526, 2014.
22. Jing Yang, Xuebin Tan, Wei-Chuan Shih, and Mark Cheng, A sandwich substrate for ultrasensitive SERS spectroscopic detection of folic acid / methotrexate, Biomedical Microdevices 16(5): 673-679 2014.
23. Fusheng Zhao, Jianbo Zeng, Md Masud Parvez Arnob, Po Sun, Ji Qi, Pratik Motwani, Mufaddal Gheewala, Chien-Hung Li, Andrew Paterson, Uli Strych, Balakrishnan Raja, Richard C. Willson, John C. Wolfe, T. Randall Lee, and Wei-Chuan Shih*, Monolithic NPG nanoparticles with large surface area, tunable plasmonics, and high-density internal hot-spots, Nanoscale 6, 8199-8207, 2014.
24. Ji Qi and Wei-Chuan Shih*, Performance of line-scan Raman microscopy for high-throughput
chemical imaging of cell population, Applied Optics 53(13), 2881-2885, 2014.
25. Ming Li, Jing Lu, Ji Qi, Fusheng Zhao, Jianbo Zeng, Jorn Chi-Chung Yu, and Wei-Chuan Shih*, Stamping surface-enhanced Raman spectroscopy for label-free, multiplexed, molecular sensing and imaging, Journal of Biomedical Optics 19(5): 050501, 2014.
26. Greggy M. Santos, Fusheng Zhao, Jianbo Zeng, and Wei-Chuan Shih*, Characterization of nanoporous gold disks for photothermal light harvesting and light-gated molecular release, Nanoscale 6(11), 5718-5724, 2014.
27. Ji Qi, Pratik Motwani, Mufaddal Gheewala, Christopher Brennan, John C. Wolfe, and Wei-Chuan Shih*, Surface-enhanced Raman spectroscopy using monolithic nanoporous gold disk substrates, Nanoscale 5: 4105-4109, 2013. (Journal cover)
28. Ji Qi, Jingting Li, and Wei-Chuan Shih*, High-speed hyperspectral Raman imaging for label-free compositional microanalysis, Biomedical Optics Express 4(11): 2376-2383, 2013.
29. Ji Qi and Wei-Chuan Shih*, Parallel Raman microspectroscopy using programmable multi-point illumination, Optics Letters 37(8): 1289-1291, 2012.
30. Szu-Te Lin, Jack C. Wolfe, John A. Dani, and Wei-Chuan Shih*, Flexible optitrode for localized light delivery and electrical recording, Optics Letters 37(11): 1-3, 2012.
31. Albert B. Andrews, Wei-Chuan Shih, Oliver C. Mullins, and N. Koyo, Molecular size determination of coal-derived asphaltene by fluorescence correlation spectroscopy, Applied Spectroscopy 65(12): 1348-1356, 2011.

Published before own group
32. Wei-Chuan Shih, Kate L Bechtel and Michael S Feld*, Intrinsic Raman spectroscopy for quantitative biological spectroscopy Part I: Theory and simulations, Optics Express 16(17): 12726-12736, 2008.
33. Kate L Bechtel, Wei-Chuan Shih and Michael S. Feld*, Intrinsic Raman spectroscopy for quantitative biological spectroscopy Part II: Experimental applications, Optics Express 16(17): 12737-12745, 2008.
34. Wei-Chuan Shih* and Albert B. Andrews, Infrared contrast of crude oil covered water surfaces, Optics Letters 33(24): 3019-3021, 2008.
35. Wei-Chuan Shih* and Albert B. Andrews, Thermal infrared contrast of native and crude oil covered water surfaces, Optics Express 16(4): 10535-10542, 2008.
36. Wei-Chuan Shih*, Kate L Bechtel and Michael S Feld, Constrained regularization: A new method for multivariate calibration, Analytical Chemistry 79(1): 234-239, 2007.
37. Obrad R. Šćepanović, Kate L. Bechtel, Abi S. Haka, Wei-Chuan Shih, Taewoon Koo, Andrew J. Berger, Michael S. Feld*, Determination of uncertainty in parameters extracted from single spectroscopic measurements, Journal of Biomedical Optics 12(6), 064012, 2007.
38. Wei-Chuan Shih*, Sang-Gook Kim and George Barbastathis, High resolution electrostatic analog tunable grating with a single-mask fabrication process, IEEE/ASME Journal of Microelectromechanical Systems 15(4), pp. 763-769, 2006.
39. Annika Enejder, Tom Scecina, Jeankun Oh, Martin Hunter, Wei-Chuan Shih, Slobadan Sasic, Gary Horowitz and Michael S.  Feld*, Raman spectroscopy for non-invasive glucose measurements, Journal of Biomedical Optics 10(3), 031114, 2005.
40. Wei-Chuan Shih*, Chee Wei Wong, Yungbae Jeon, Sang-Gook Kim and George Barbastathis, MEMS tunable gratings with analog actuation, Information Sciences 149(1-3), 31-40, 2003.

Books: 

Wei-Chuan Shih**, “Hybrid fabrication makes better plasmonic nanostructures for SERS,” Photonics Spectra, August, 2013.

Wei-Chuan Shih, Kate L. Bechtel, and Michael S Feld, “Quantitative Biological Raman Spectroscopy,” in Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues, Editor: Valery V. Tuchin (Taylor & Francis 2008).

Wei-Chuan Shih, Kate L Bechtel, Michael S Feld, Mark A Arnold, Gary W Small, “Introduction to spectroscopy for noninvasive glucose sensing,” in Analytical Chemistry of In Vivo Glucose Measurements; Cunningham, D.; Stenken, JA, Eds.; Wiley Chemical Analysis Series (2009).

Wei-Chuan Shih, Kate L Bechtel, Michael S Feld, “ Non-invasive glucose sensing with Raman spectroscopy,” in Analytical Chemistry of In Vivo Glucose Measurements; Cunningham, D.; Stenken, JA, Eds.; Wiley Chemical Analysis Series (2009).

Patent/Patent Applications: 

62031516, Fabrication of lenses by droplet formation on a pre-heated surface (Provisional application). Inventor: Wei-Chuan Shih and Yulung Sung; Assignee: U. Houston
62004131, Nanoporous gold and silver nanoparticles and substrates for biomolecular sensing (Provisional application). Inventor: Wei-Chuan Shih and Richard C Willson; Assignee: U. Houston
61985984, Method of stamping surface-enhanced Raman spectroscopy for label-free, multiplexed, molecular sensing and imaging (Provisional application). Inventor: Wei-Chuan Shih and Ming Li; Assignee: U. Houston
61827192, Integrated thin-film optrode (Provisional application). Inventor: John C Wolfe, Mufaddal Gheewala, Wei-Chuan Shih; Assignee: U. Houston
61609451 Nanoporous gold nanoparticles as high-payload molecular cargo for cancer treatment and ultrahigh surface-to-volume sensor applications (Patent pending). Inventor: Wei-Chuan Shih. Assignee: U. Houston.
61585927 “Method and system for Raman microspectroscopy (Patent pending). Inventors: Wei-Chuan Shih. Asignee: U. Houston
US8661663 Method for manufacturing a multimodal neural probe. Inventors: John C Wolfe and Wei-Chuan Shih. Asignee: U. Houston.
US6975459 Micro-actuated adaptive diffractive composites. Inventors: G Barbastathis, SG Kim, Wei-Chuan Shih, CW Wong, YB Jeon. Asignee: MIT
US8124931 Method and apparatus for oil spill detection. Inventors: AB Andrews, Wei-Chuan Shih, M Clayton, OC Mullins. Asignee: Schlumberger Technology Corporation
US8362429 Method and apparatus for oil spill detection. Inventors: AB Andrews, Wei-Chuan Shih, M Clayton, OC Mullins. Asignee: Schlumberger Technology Corporation
US 8355767 Raman spectroscopy for non-invasive glucose measurements. Inventors: M. Hunter, A. Enejder, T. Scecina, M. Feld, Wei-Chuan Shih. Asignee: MIT

Refereed Conference Proceedings: 

1. Yu-Lung Sung, Fusheng Zhao, Jingting Li, and Wei-Chuan Shih, “Gold nanoparticle decorated AAO filter membrane for SERS sensing of urine acetaminophen,” IEEE Sensors, Oct 2016. 2. Wei-Chuan Shih,* Fusheng Zhao, Ousamma Zenasni, and Masud Arnob, “Surface-enhanced near-infrared absorption (SENIRA) spectroscopy,” IEEE Sensors, Oct 2016. 3. Fusheng Zhao, Suyan Qiu, and Wei-Chuan Shih, “Nanoplasmonic sensing on DNA topological structure functionalized nanoporous gold disks,” IEEE Optical MEMS and Nanophotonics (OMN), Aug 2016. 4. Jingting Li, Ming Li, Yong Du, Greggy M. Santos, Chandra Mohan, Wei-Chuan Shih, “Raman and surface-enhanced Raman spectroscopy for renal condition monitoring,” Proceedings of SPIE, 2016. 5. Greggy M. Santos, Felipe Ibanez, Fusheng Zhao, Debora Rodrigues, Wei-Chuan Shih, “Photothermal inactivation of bacteria on plasmonic nanostructures,” Proceedings of SPIE, 2016. 6. Suyan Qiu, Fusheng Zhao, Greggy M. Santos, Wei-Chuan Shih, “Plasmonic biosensor for label-free malachite green detection,” Proceedings of SPIE, 2016. 7. Jingting Li, Ming Li, Greggy M. Santos, Fusheng Zhao, Wei-Chuan Shih, “Photothermal generation of microbubbles on plasmonic nanostructures for flow manipulation inside microfluidic channels,” Proceedings of SPIE, 2016. 8. Gauri Bhave, Fusheng Zhao, Jingting Li, and Wei-Chuan Shih, “Wavelength tunable plasmon enhanced photoluminescence from quantum dots”, IEEE Optical MEMS and Nanophotonics (OMN), Aug 2015. 9. Masud Arnob, Fusheng Zhao, and Wei-Chuan Shih, “Modeling Nanoporous Gold Plasmonic Nanoparticles: Calculation of Optical Properties”, IEEE NANO, Jul 2015. 10. Fusheng Zhao, Jianbo Zeng, Masud Arnob, Greggy Santos, Wei-Chuan Shih, "Monolithic nanoporous gold disks with large surface area and high-density plasmonic hot-spots", in Plasmonics in Biology and Medicine XII, Tuan Vo-Dinh; Joseph R. Lakowicz, Editors, Proceedings of SPIE Vol. 9340 (SPIE, Bellingham, WA 2015), 93400B. 11. Ming Li, Yong Du, Fusheng Zhao, Jianbo Zeng, Greggy Santos, Chandra Mohan, Wei-Chuan Shih, "Stamping SERS for creatinine sensing", in Plasmonics in Biology and Medicine XII, Tuan Vo-Dinh; Joseph R. Lakowicz, Editors, Proceedings of SPIE Vol. 9340 (SPIE, Bellingham, WA 2015), 934004. 12. Ji Qi, Jianbo Zeng, Fusheng Zhao, Greggy Santos, Steven Lin, Balakrishnan Raja, Ulrich Strych, Richard Willson, Wei-Chuan Shih, "Label-free monitoring of individual DNA hybridization using SERS", in Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XII, Alexander N. Cartwright; Dan V. Nicolau, Editors, Proceedings of SPIE Vol. 9337 (SPIE, Bellingham, WA 2015), 93370D. 13. Ming Li, Fusheng Zhao, Jianbo Zeng, Greggy Santos, Wei-Chuan Shih, "Label-free, multiplexed, molecular sensing and imaging by stamping SERS", in Optical Diagnostics and Sensing XV: Toward Point-of-Care Diagnostics, Gerard L. Coté, Editors, Proceedings of SPIE Vol. 9332 (SPIE, Bellingham, WA 2015), 93320E. 14. Ji Qi, Narendran Sudheendran, Chih Hao Liu, Greggy Santos, Eric D. Young, Alexander Lazar, Dina Lev, Raphael Pollock, Kirill V. Larin, Wei-Chuan Shih, "Raman spectroscopy complements optical coherent tomography in tissue classification and cancer detection", in Optical Biopsy XIII: Toward Real-Time Spectroscopic Imaging and Diagnosis, Robert R. Alfano; Stavros G. Demos, Editors, Proceedings of SPIE Vol. 9318 (SPIE, Bellingham, WA 2015), 931807. 15. Ming Li, Fusheng Zhao, Jianbo Zeng, Greggy Santos, Wei-Chuan Shih, "Monolithically integrated microfluidic nanoporous gold disk (NPGD) surface-enhanced Raman scattering (SERS) sensor for rapid and label-free biomolecular detection", in Microfluidics, BioMEMS, and Medical Microsystems XIII, Bonnie L. Gray; Holger Becker, Editors, Proceedings of SPIE Vol. 9320 (SPIE, Bellingham, WA 2015), 93200K. 16. Greggy M. Santos, Fusheng Zhao, Jianbo Zeng, Wei-Chuan Shih, "Photothermal light harvesting and light-gated molecular release by nanoporous gold disks", in Dynamics and Fluctuations in Biomedical Photonics XII, Valery V. Tuchin; Kirill V. Larin; Martin J. Leahy; Ruikang K. Wang, Editors, Proceedings of SPIE Vol. 9322 (SPIE, Bellingham, WA 2015), 93220J. 17. Szu-Te Lin; Mufaddal Gheewala; John A Dani; John C Wolfe; Wei-Chuan Shih, “Flexible optitrode for localized light delivery and electrical recording,” Proc. SPIE 8565, Photonic Therapeutics and Diagnostics IX, 85655Y (8 March 2013); doi: 10.1117/12.2005707. 18. Ji Qi, Pratik Motwani, John C Wolfe and Wei-Chuan Shih, “Monolithic porous gold nanostructures as surface-enhanced Raman spectroscopy substrates for molecular and biosensing,” Proc. SPIE 8597, Plasmonics in Biology and Medicine X, 85970I (February 21, 2013); doi:10.1117/12.2005727. 19. Ji Qi and Wei-Chuan Shih, “Sparse-sampling parallel Raman/SERS microspectroscopy for high-throughput molecular analysis of micro and nanoparticles,” Proc. SPIE 8587, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XI, 85871N (February 22, 2013); doi:10.1117/12.2005718. 20. Ji Qi, Pratik Motwani, John C Wolfe and Wei-Chuan Shih, “High throughput Raman and surface-enhanced Raman microscopy,” Proc. SPIE 8219, Biomedical Vibrational Spectroscopy V: Advances in Research and Industry, 821903 (February 9, 2012); doi:10.1117/12.908971. 21. Yingying Li, Wei-Chuan Shih, Zhu Han and Wotao Yin, "Oil spill sensor using multispectral infrared imaging via l1 minimization," ICASSP, Prague CZ, May 2011, DOI: 10.1109/ICASSP.2011.5946670. 22. Szu-Te Lin, Mufaddal Gheewala, John C Wolfe, John A Dani and Wei-Chuan Shih, “A flexible optrode for deep brain neurophotonics,” IEEE/EMBS International Conference on Neural Engineering, Cancun, Mexico, May 2011, DOI: 10.1109/NER.2011.5910644. 23. Wei-Chuan Shih, A Ballard Andrews and Matthew Clayton, “Offshore stand-off oil spill monitoring using passive optical imaging,” Proc. SPIE 7312, Advanced Environmental, Chemical, and Biological Sensing Technologies VI, 73120V (1 May 2009); doi: 10.1117/12.818738. 24. Wei-Chuan Shih, Kate L Bechtel and Michael S Feld, “Intrinsic Raman spectroscopy improves analyte concentration measurements in turbid media,” Biomedical Optics Topical Meeting by Optical Society of America, Fort Lauderdale, FL, Mar 2006; DOI: 10.1364/BIO.2006.MC7. 25. Wei-Chuan Shih, Carlos Hidrovo, Sang-Gook Kim and George Barbastathis, “Optical diversity by nanoscale actuation,” IEEE NANO, San Francisco CA, 2003. 26. Wei-Chuan Shih, Chee Wei Wong, Yong Bae Jeon, Sang-Gook Kim and George Barbastathis “Electrostatic and piezoelectric analog tunable diffractive gratings,” Lasers and Electro-Optics (CLEO), Long Beach CA, May 2002; DOI: 10.1109/CLEO.2002.1033451. 27. Wei-Chuan Shih, Chee Wei Wong, Yong Bae Jeon, Sang-Gook Kim, Martin A Schmidt, Salil Desai, Dennis M Freeman, Arnab Sinha, Gregory Nielson, and George Barbastathis, “Analog tunable diffractive grating with milliradian resolution,” Optical Fiber Communication Conference (OFC), Anaheim CA, Mar 2002; DOI: 10.1109/OFC.2002.1036296.

Presentations: 

Invited Seminar Talks 1. “Opto-Analytical Spectroscopy, Imaging, and Sensing (OASIS),” Department of Materials Science and Engineering, Nanyang Technological University, Aug 2016. 2. “Opto-Analytical Spectroscopy, Imaging, and Sensing (OASIS),” National University of Singapore, Aug 2016. 3. “Opto-Analytical Sensing, Imaging, and Stimulation (OASIS),” Department of Electrical and Computer Engineering, North Carolina State University, Mar 2016. 4. “Opto-Analytical Sensing, Imaging, and Stimulation (OASIS),” Department of Mechanical Engineering, Columbia University, Feb 2016. 5. “Opto-Analytical Sensing, Imaging, and Stimulation (OASIS),” OSA Chapter, Rice University, Feb 2015. 6. “Opto-Analytical Sensing, Imaging, and Stimulation (OASIS),” School of Dentistry, University of Texas Health, Jan 2016. 7. “Opto Analytical Sensing, Imaging, and Stimulation,” Neural Engineering Workshop, Rice University, Oct 2015. 8. “Light-based molecular sensing and imaging for translational biophotonics,” Seminar, CREOL, University of Central Florida, Apr. 2015. 9. “Novel Nanomaterials and Instruments for Translational Biophotonics Applications,” Seminar, ECE Department, University of Minnesota, Feb. 2015. 10. “Novel plasmonic nanomaterials and instruments for biomedical applications,” Workshop on Light-Driven Processes in Bio-Inspired Materials, Rice University, Huston TX, Dec. 2014. 11. “Mesoporous plasmonic nanoparticles for Biomedical Applications,” Department of Biomedical Engineering, Johns Hopkins University, Baltimore MD, Jul. 2014. 12. “Mesoporous plasmonic nanoparticles for Biomedical Applications,” National Institute of Aging, National Institute of Health, Baltimore MD, Jul. 2014. 13. “Mesoporous plasmonic nanoparticles for sensing and imaging,” Department of Photonics, National Jiao Tung University, Hsinchu Taiwan, Jun. 2014. 14. “Mesoporous plasmonic nanoparticles,” Department of Mechanical and Automation Engineering and Department of Physics, Chinese University of Hong Kong, HK SAR China, Jun. 2014. 15. “Biomimetic plasmonic quasi nanocrystals,” Fitzpatrick Center of Photonics, Duke University, Durham NC, Apr. 2014. 16. “Label-free molecular sensing using Raman and SERS,” Department of Electrical and Computer Engineering, University of Texas at Arlington, Arlington TX, Mar. 2014. 17. “Label-free molecular sensing using Raman and SERS,” Department of Electrical and Computer Engineering, Wayne State University, Detroit MI, Nov. 2013. 18. “Novel microscopy instrument and nanostructured substrates for plasmonic molecular sensing and imaging,” Department of Electrical and Computer Engineering, University of Nevada at Reno, Reno NV, Feb. 2013. 19. “Photonic technologies for molecularly-specific sensing, imaging and stimulation,” Department of Chemistry, University of California at Santa Cruz, Santa Cruz CA, Feb. 2013. 20. “Photonic technologies for molecularly-specific sensing, imaging and stimulation,” Department of Biomedical Engineering, Vanderbilt University, Nashville TN, May 2013. 21. “Photonic technologies for molecularly-specific sensing, imaging and stimulation,” Department of Mechanical Engineering, Virginia Commonwealth University, Richmond VA, Oct. 2012. 22. “Photonic technologies for molecularly-specific sensing, imaging and stimulation,” Department of Biomedical Engineering, Texas A&M University, College Station TX, Sept. 2012. 23. “Quantitative Bio Raman Spectroscopy and Imaging”, Department of Mechanical Engineering, University of Houston, Houston TX, Jan. 2011. 24. “Toward integrated sensing and diagnosis,” Schlumberger, Sugar Land TX, Jun. 2010. 25. “Toward integrated sensing and diagnosis,” Department of Electrical Engineering, National Taiwan University, Taipei Taiwan, Jan. 2010. 26. “Toward integrated sensing and diagnosis,” Department of Mechanical Engineering, National Chiao Tung University, Hsin-Chu Taiwan, Jan. 2010. 27. “Optical sensing and Micro/Nanotechnology,” Schlumberger, Sugar Land TX, May 2009. 28. “Toward intelligent optical sensing and diagnosis,” Department of Electrical and Computer Engineering, University of Houston, Houston TX, Mar. 2009. 29. “Toward intelligent optical sensing and diagnosis,” Department of Mechanical and Automation Engineering, Chinese University of Hong Kong, HK SAR China, Feb. 2009. 30. “Toward intelligent optical sensing and diagnosis,” Department of Mechanical Engineering, Hong Kong University, HK SAR China, Feb. 2009. 31. “Label-free, non-invasive sensing and diagnosis using optical spectroscopy,” Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Oct. 2008. 32. “How sweet are you?”, Department of Electrical and Computer Engineering, University of Minnesota, Feb. 2008. 33. “Quest for carbohydrates and hydrocarbons,” Department of Electrical and Computer Engineering, Tufts University, Jan. 2008. 34. “Quantitative biological Raman spectroscopy,” MIT Modern Optics and Spectroscopy (MOS) Seminar, Massachusetts Institute of Technology, Cambridge MA, Mar. 2006. 35. “Diffractive optical elements with analog micromechanical actuation,” MIT Microphotonics Center, Cambridge, MA, Apr. 2002.

News: 

Major grants:

- DOI Award 2015
- NIH R21 grant 2014
- NSF CAREER Award 2012
- NASA CAREER Award 2012
- GoMRI-RFPII 2012

Multiple positions for PhD Research Assistant and Postdoc (Start immediately):
Suitable expertise: Optics, photonics, plasmonics, spectroscopy, imaging, FDTD, microfluidics, nanofabrication, microfabrication, biophotonics, biodemical optics.

location

Dept. of Electrical & Computer Engineering
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4726 Calhoun Rd
Houston, TX 77004-4005
Phone: 713-743-4400
Fax: 713-743-4444
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